CRISPR DNA "shredder"

New DNA 'shredder' technique goes beyond CRISPR's scissors

CRISPR DNA "shredder"

An international team has unveiled a new CRISPR-based tool that acts more like a shredder than the usual scissor-like action of CRISPR-Cas9. The new approach, based on Type I CRISPR-Cas3, is able to wipe out long stretches of DNA in human cells with programmable targeting, and has been shown to work in human cells for the first time.


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