GenomeWeb: Cartana, Lunaphore Form In Situ Sequencing Technology Partnership
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NEW YORK (GenomeWeb) — Swedish startup Cartana has signed an agreement to integrate its in situ RNA sequencing (ISS) technology with Lunaphore Technologies' microfluidic tissue processor technology.
Cartana's technology, which was originally developed in the lab of Stockholm University's Mats Nilsson, is based on using barcoded padlock probes to target genes of interest. The probes target cDNA and are amplified in situ using rolling circle amplification, followed by sequencing-by-ligation, also directly on the tissue.
Under the terms of the deal, the companies will work with Nilsson to join the technology with Lunaphore's Fast Fluidic Exchange rapid immunohistochemistry platform in order to develop hardware for automated sequencing and imaging cycles.
